Abstract The mechanisms of bifurcation, a key step in thyroid development, are largely unknown.Here we find three zebrafish lines from a forward genetic screening with similar thyroid dysgenesis phenotypes and identify a stop-gain mutation in hgfa and two missense mutations in met by positional cloning from these zebrafish lines.The elongation of t
Safety concerns expressed by micro-mobility users seem to practically constrain the use and flexibility of these new modes.This paper introduces a new, parametric agent-based modeling approach for simulating micro-mobility, using MATSim as a platform.Perceived safety is introduced as a factor, which affects travel behavior of micro-mobility modes i
Grouper iridovirus (GIV) belongs to the genus Ranavirus of the family Iridoviridae; the genomes of such viruses contain an anti-apoptotic caspase recruitment domain (CARD) gene.The GIV-CARD gene encodes a ORG STEVIA NATURAL protein of 91 amino acids with a molecular mass of 10,505 Daltons, and shows high similarity to other viral CARD genes and hum
Abstract Background The functions of proteins are closely related to their subcellular locations.In the post-genomics era, the amount of gene and protein data grows exponentially, which necessitates the prediction of subcellular localization by computational means.Results This paper proposes mitigating the computation burden of alignment-based appr